By Philip Bittihn
This award-winning thesis investigates the mechanisms underlying cardiac arrhythmia improvement and termination from a completely new viewpoint. via viewing the guts as a fancy process, the writer makes use of theoretical instruments from nonlinear dynamics mixed with numerical simulations and experiments to accomplish insights into the connection among its constitution and dynamics, thereby paving the best way in the direction of cutting edge low-energy defibrillation innovations. The paintings tackles, between different issues: the impact of substrate heterogeneity at the spatial-temporal dynamics of cardiac arrhythmias and ways that susceptible pulsed electrical fields can be utilized to regulate those dynamics in heterogeneous cardiac tissue. The long term imaginative and prescient of this learn is to switch the present technique of utilizing painful and occasionally tissue destructive electrical surprise – at the moment the one trustworthy strategy to terminate life-threatening traumatic inflammation – by means of a extra sophisticated yet both powerful intervention. The e-book maps out a few promising learn instructions for biophysicists and clinical researchers engaged on the origins and remedy of cardiac arrhythmias.
Read or Download Complex Structure and Dynamics of the Heart PDF
Best cardiology books
Angiogenesis study is without doubt one of the so much quick constructing components in biomedicine. it really is thought of to be a typical denominator in society's most vital ailments and pharmaceutical businesses are racing to boost new angiogenesis-based medicines. This quantity makes a speciality of the genetic keep an eye on of angiogenesis, either in people and version organisms, and may be a beneficial source to all researchers within the box, together with the basics of the method in addition to staff in biotechnology.
This ebook provides the present taking into account overseas specialists in regards to the underlying mechanisms of cardiovascular chance in addition to the pathogenesis and pathophysiology of impaired huge arterial stiffness and lowered huge arterial distensibility. It additionally demonstrates the reason for the current method of the administration and remedy of hypertensive illnesses and atherosclerosis.
Speeded up heart problems is a widespread hassle of continual kidney sickness. people with proof of renal practical impairment usually tend to die of cardiovascular occasions than to development to finish level renal ailment. This dating, which has been termed the cardiorenal syndrome, exists no matter if impairment of renal functionality is a final result of basic renal parenchymal or fundamental center disorder.
The guide of Venous issues, first released in 1996, is a guide for all clinicians and surgeons who're concerned with the research, overview, or administration of venous and lymphatic ailments or malformations. those issues comprise varicose veins, venous ulcers, DVT, lymphedema, and pulmonary embolism, in addition to harm to the veins via trauma or tumor development.
Extra info for Complex Structure and Dynamics of the Heart
16) in the same section. e. they fix the normal fluxes n ·D∇u on the boundary ∂D. As will be shown in Sect. , rectangles in cartesian coordinates or (fractional) annuli in polar coordinates. For arbitrarily shaped domains D, there is no such natural way of imposing zero flux on the domain boundary. In this case, one usually resorts to more complex and computationally intensive numerical schemes like finite-volume or finite-element methods (see Sect. 3 of Ref.  and references therein). In Ref.
Barkley, D. (1994). Euclidean symmetry and the dynamics of rotating spiral waves. Physical Review Letters, 72, 164–167. 106. , & Otani, N. F. (2004). Preventing alternans-induced spiral wave breakup in cardiac tissue: An ion-channel-based approach. Physical Review E, 70, 061903. 107. Biktasheva, I. , Biktashev, V. , & Foulkes, A. J. (2010). Computation of the drift velocity of spiral waves using response functions. Physical Review E, 81, 066202. 108. Lyapunov, A. M. (1892). The general problem of the stability of motion.
107. Biktasheva, I. , Biktashev, V. , & Foulkes, A. J. (2010). Computation of the drift velocity of spiral waves using response functions. Physical Review E, 81, 066202. 108. Lyapunov, A. M. (1892). The general problem of the stability of motion. D. thesis. 109. Oseledec, V. I. (1968). A multiplicative ergodic theorem. Ljapunov characteristic numbers for dynamical systems. Transaction of the Moscow Mathematical Society, 19, 197–231. 110. -M. (1980). Lyapunov characteristic exponents for smooth dynamical systems and for hamiltonian systems; a method for computing all of them.
Complex Structure and Dynamics of the Heart by Philip Bittihn