By Andrea Natale, Jose Jalife
This crucial new ebook offers developments within the therapy and prevention of Atrial traumatic inflammation (AF). The reader is supplied with the newest info that's severely vital within the day-by-day care and for the aptitude therapy of sufferers with AF. every one bankruptcy offers with a special point of AF and every bankruptcy is authored by means of the world over well-known specialists within the evolving box of cardiac electrophysiology. This booklet is a unmarried resource that offers a multi-perspective examine and method of AF. simply because AF is so conventional and impacts all parts of drugs, the knowledge during this booklet could be beneficial to all these within the clinical box.
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Extra resources for Atrial Fibrillation: From Bench to Bedside (Contemporary Cardiology)
Wyse DG, Waldo AL, DiMarco JP, Domanski MJ, Rosenberg Y, Schron EB, Kellen JC, Greene HL, Mickel MC, Dalquist JE, Corley S D. Relationships between sinus rhythm, treatment, and survival in the atrial fibrillation follow-up investigation of rhythm management (AFFIRM) study. Circulation. 2004;109:1509–1513. 8. Weerasooriya R, Jais P, Le Heuzey J-Y, Scavee C, Choi K-J, Macle L, Raybaud F, Hocini, Shah D, Lavergne T, Clementy J, Haissaguerre M. Cost analysis of catheter ablation for paroxysmal atrial fibrillation.
Arrhythmia control involves antiarrhythmic or atrioventricular (AV) nodal blocking medications. 56 These benefits must be weighed against the potentially dangerous side effects associated with antiarrhythmic medications. An alternative method of AF management is rate control strategies with AV nodal blocking agents. 56 In general, no differences in outcomes were detected between the two treatments. 37,56 Costs, on the other hand, were less with a rate control strategy. Both RACE and AFFIRM demonstrated cost savings in the rate control arm, even after sensitivity analyses.
Anticoagulation Another crucial consideration in long-term AF management is anticoagulation. 64–67 Despite this impressive efficacy, anticoagulation comes with a risk of hemorrhage. Warfarin use requires careful and frequent monitoring to ensure therapeutic levels of anticoagulation and to Chapter 2 Economic Costs avoid bleeding complications. Frequent laboratory testing is necessary to maintain a normalized prothrombin clotting time ratio (INR, international normalized ratio) of 2 to 3. K. 38 Although these costs include all medications used in AF therapy, they point to the significant cost impact of anticoagulation Anticoagulation complications also affect costs.
Atrial Fibrillation: From Bench to Bedside (Contemporary Cardiology) by Andrea Natale, Jose Jalife